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Chronic Outward Force

(Stent)

Chronic outward force (COF) is a critical performance parameter for self-expanding stents. It describes the sustained radial pressure exerted by the stent against the vessel wall over time, directly influencing vessel patency, tissue response, and long-term clinical outcomes. Accurate measurement of COF is essential to balance mechanical support with biological compatibility, ensuring that stents provide reliable function without excessive vessel trauma.

At our testing facility, we provide comprehensive COF evaluation services in accordance with ASTM F3067: Standard Guide for Radial Loading of Balloon Expandable and Self-Expanding Vascular Stents, supporting both innovation and regulatory compliance:

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  • Radial Force Measurement:
    Precise quantification of chronic outward force and radial resistive force under controlled loading conditions.

 

  • Physiological Simulation:
    Testing in anatomically relevant fixtures and environments to replicate in vivo deployment and vessel interaction.

 

  • Material & Design Assessment:
    Evaluation of stent geometry, alloy properties, and surface treatments to understand their impact on COF.

 

  • Regulatory Alignment:
    Protocols structured to meet ASTM F3067, ISO 25539‑2, and FDA guidance, ensuring acceptance in global submissions.
  • Patient Safety First:
    Proper COF ensures stents maintain vessel patency without causing excessive vessel injury or restenosis.

 

  • Accelerated Market Access:
    Compliance-driven testing streamlines regulatory pathways and builds confidence with regulators and clinicians.

 

  • Innovation Support:
    Detailed COF data empowers manufacturers to optimize stent designs and advance next-generation vascular technologies.

 

By combining advanced instrumentation, expert analysis, and strict adherence to ASTM F3067, we help manufacturers validate the chronic outward force performance of vascular stents. Partnering with us means confidence in compliance, innovation, and patient protection.

Workflow

How we work:

A clear, three-step workflow—ensures a reliable, data-driven progress.

Feasibility
Study

Performance
Charaterization

Full approval-
relevant studies

Your journey with ac.biomed:

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1.
Service Request

2.
Information Provision

3.
NDA

1.
Service Request
2.
Information Provision
3.
NDA
4.
Service Requirements
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4.
Service Specification

5.
Quotation

6.
Order

7.
Order Confirmation
5.
Service Specification
6.
Quotation
7.
Order
8.
Order Confirmation
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8.
Test Plan

9.
Test Plan Approval

10.
Test Execution

11.
Test Report
9.
Test Plan
10.
Test Plan Approval
11.
Test Execution
12.
Test Report

Our strengths

“Outstanding service, reliable support, genuine customer closeness and open communication – this is our shared path to success.”

Quality

ac.biomed provides
quality services.

Certificate
ISO 17025
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Certificate
ISO 9001:2015
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Move forward
with ac.biomed

We want to hear from you. Whether you‘re a prospective client, a professional interested in joining our team, or simply someone interested in our work, send us a note.

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